Last weekend’s FA Cup hat-trick hero Tom Eaves continues in attack while Matthew Pennington starts a second successive league fixture as part of the back line.
Former Hull City midfielder Tom Cairney is on the Fulham bench, but former Tigers loanee Michael Hector starts having recently completed a move from Chelsea.
Hull City: George Long, Eric Lichaj, Jordy de Wijs, Reece Burke, Tom Eaves, Kamil Grosicki, Jarrod Bowen, Matthew Pennington, Jackson Irvine, Leonardo Da Silva Lopes, Herbie Kane.
Subs: Matt Ingram, Ryan Tafazolli, Daniel Batty, George Honeyman, Josh Bowler, Brandon Fleming, Keane Lewis-Potter.
Fulham: Marek Rodak, Michael Hector, Denis Odoi, Kevin McDonald, Aleksandar Mitrovic, Tim Ream, Bobby Decordova-Reid, Ivan Cavaleiro, Cyrus Christie, Anthony Knockaert, Josh Onomah.
Subs: Magnus Norman, Alfie Mawson, Stefan Johansen, Tom Cairney, Harry Arter, Joe Bryan, Jay Stansfield.
Referee: Mr M. Donohue.