With defenders Michael Hector, Ola Aina and Fikayo Tomori ineligible to face their parent club, and midfielder Seb Larsson serving the first of a two-game ban, Adkins will be forced to make a number of changes and he was giving very little away at his pre-match meeting with the press this week.
“The three Chelsea lads can’t play, nor can Seb Larsson, so that’s four players who have been regulars for us,” said Adkins.
“That gives other players an opportunity. I know what we’re going to do, but we’ll leave people to discover that when the teamsheet goes in 75 minutes before kick-off.
“It’s a challenging scenario, and like I’ve said we will need a little bit of cup magic to help us.”
Adkins will wait on the fitness of Michael Dawson as the club captain continues his recovery from a groin injury, while Kamil Grosicki is another who will hope to recover from injury in time.
Chelsea will be without Ross Barkley, David Luiz and Tiemoue Bakayoko but striker Alvaro Morata is likely to be involved at some stage as he works his way back towards full fitness.